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Sarah J. Ewing

  • Provost & VP, Student Exp.
    Academic Affairs
  • Molecular and Cellular Biology (BIOL 122)
  • Molecular and Cellular Biology Lab (BIOL 123)
  • Cellular Biochemistry (BIOL 373)
  • Cellular Biochemistry Lab (BIOL 374)
  • Biology of Cancer (BIOL 495)
  • Ph.D. in Comparative Biomedical Sciences, December 2007 North Carolina State University, Raleigh, NC. Dissertation: "C/EBPbeta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19Arf". Advisor: Dr. Robert C. Smart.
  • B.S. in Biology, minor in Chemistry, May 2001, Penn State Behrend, The Erie College, Erie, PA. University Schreyer Scholar Thesis:  "Genetic Diversity in Black Cherry (Prunus serotina) Using Microsatellite DNA Markers". Advisor: Dr. Michael Campbell.
  • Dean, Morosky College of Health Professions and Sciences, Gannon University, Erie, PA (January 2018 - Present)
  • Interim Dean, Morosky College of Health Professions and Sciences, Gannon University, Erie, PA (January 2017 - December 2017)
  • Associate Dean, Morosky College of Health Professions and Sciences, Gannon University, Erie, PA (July 2015 - December 2016)
  • Chairperson, Biology Department, Gannon University, Erie, PA (July 2013 - December 2016)
  • Director of Pre-Professional Programs, Gannon University, Erie, PA (2009 - 2013)
  • Associate Professor of Biology, Gannon University, Erie, PA (August 2015 - Present)
  • Assistant Professor of Biology, Gannon University, Erie, PA (2009 - 2015)
  • Lecturer in Biology, Penn State Behrend, the Erie College, Erie, PA (2007 - 2009)
  • Council of Undergraduate Research (CUR) (2012 - Present)
  • Sigma Xi, The Scientific Research Society (Northwest Pennsylvania Chapter) (2008 - Present)
  • American Association for the Advancement of Science (AAAS) (2005 - Present)

Peer Reviewed Articles                                   * Denotes undergraduate student co-author

  • Ganger, M. T., Dietz, G. D., Headley, P., Ewing, S. J. (2020) Application of the common base method to regression and analysis of covariance (ANCOVA) in qPCR experiments and subsequent relative expression calculation. BMC Bioinformatics, 21(1): 423 (doi: 10.1186/s12859-020-03696-y).
  • Ganger, M.T., *Hiles, R., *Hallowell, H., *Cooper, L., *McAllister, N., *Youngdahl, D., *Alfieri, J., Ewing, S.J. (2019). A soil bacterium alters sex determination and rhizoid development in gametophytes of the fern Ceratopteris richardii. AoB PLANTS, 11: plz012; (doi: 10.1093/aobpla/plz012).
  • Ganger, M. T., Dietz, G. D., Ewing, S. J. (2017) A common base method for analysis of qPCR data and the application of simple blocking in qPCR experiments. BMC Bioinformatics, 18(1):534 (doi: 10.1186/s12859-017-1949-5).
  • Ganger, M., *Girouard, J., *Smith, H., *Bahny, B., Ewing, S. (2015). Antheridiogen and abscisic acid affect conversion and ANI1 expression in Ceratopteris richardii gametophytes. Botany, 93(2): 109-116, doi: 10.1139/cjb-2014-0202.
  • *Smerker, H., Ewing, S. (2014). Weaning and adaptation of SH-SY5Y cells to low-glucose media for manganese exposure studies. In M. Lemaster (Ed.) Proceedings of the National Conference on Undergraduate Research (pp. 449-459). Asheville, NC: University of North Carolina - Asheville.
  • *McGivern, J.J., Ganger, M.T., Ewing, S.J. (2013). FT and NPR1 expression patterns in Arabidopsis thaliana during flowering and in response to alicylate. BIOS. 84(4): 241-249.
  • *Groesch, M., *Amata, N., Ewing, S. (2013). Elucidating the effects of manganese on monoamine neurotransmitter metabolism and dopaminergic cell viability. In M. Lemaster (Ed.) Proceedings of the National Conference on Undergraduate Research (pp. 649-657). Asheville, NC: University of North Carolina - Asheville.
  • Ewing, S. J., Zhu, S. Zhu, F. House, J. S. & Smart, R. C. (2008). C/EBPb represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19Arf. Cell Death and Differentiation, 15(11), 1734-1744, doi: 10.1038/cdd.2008.105.
  • Yoon, K., Zhu, S., Ewing, S.J., Smart, R.C. (2007) Decreased survival of C/EBPb-deficient keratinocytes is due to aberrant regulation of p53 levels and function. Oncogene, (26):360-367, doi: 10.1038/sj.onc.1209797
  • Shim, M., Powers, K.L., Ewing, S.J., Zhu, S., Smart, R.C.  (2005) Diminished expression of C/EBPa in skin carcinomas is linked to oncogenic Ras and re-expression of C/EBPa in carcinoma cells inhibits proliferation. Cancer Res, 65(3):861-867.
  • Moorefield, K.S., Fry, S.J., Horowitz, J.M.  (2004) Sp2 DNA-binding activity and trans-activation are negatively regulated in mammalian cells. J Biol Chem, 279(14):13911-13924, doi: 10.1074/jbc.M313589200.

Book Chapters:

  • Smart, R.C., Ewing, S.J., & Loomis, K.D. (2008). Carcinogenesis.  In R. C. Smart & E. Hodgson (Eds.), Molecular and biochemical toxicology (pp. 537-586). New York: John Wiley and Sons.

Published Abstracts:

  • Ganger, M., *Smith, H., *Girouard, J., *Bahny, B., Ewing, S. (2013) Antheridiogen and abscisic acid influence conversion and ANI1 expression in the homosporous fern Ceratopteris richardii. Botany 2013, New Orleans, LA.
  • Ewing, S.J., Zhu, S., Smart, R.C. (2007) C/EBPb regulates p53 downstream of DNA damage independent of oncogenic stress and p19Arf.  American Association for Cancer Research Annual Meeting 2007, April 2007, Los Angeles, CA.
  • Fry, S.J., Campbell, M.A. (2001) Determining Genetic Diversity in Black Cherry, Prunus serotina, using Microsatellite Markers. International Plant and Animal Genomes Conference, January 2001, San Diego, CA.
  • Association of Schools Advancing Health Professions (ASAHP), Interprofessional Education Task Force, Member (2020 – Present)
  • Association of Schools Advancing Health Professions (ASAHP), Clinical Education Task Force, Member (2020 – Present)
  • Northwest Pennsylvania Area Health Education Center, Board Member, Erie, PA (2019 – Present)
  • UPMC Hamot Patient Quality & Safety Committee Member, Erie, PA (2018 – Present)
  • United Way Young Leaders Society, Member (2010 – Present)
  • Annual Participant in G.I.V.E. Day, Erie, PA (Fall of 2009 - Present)
  • Hooked on Books for Kids, Board Member, Erie, PA (2015 – 2019)
  • Northwestern Pennsylvania Regional Chapter of Sigma Xi, President (May 2013 – May 2015)
  • Northwestern Pennsylvania Regional Chapter of Sigma Xi, Secretary (May 2010 – 2013)
  • Coordinator of the Western Pennsylvania Local Area Network for the Northeast Association of Advisors for the Health Professions (NEAAHP) (2012 – 2013)
Sarah           J. Ewing

+1 8148717752
Office: MAIN 205

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