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The activities of the Research Initiation Award (RIA) strategy will help to realize the second objective of the TRANSFORM grant which is to increase the number of Gannon female faculty achieving advancement in rank. The research initiation award will provide resources for early- or mid- career, female STEM faculty as they pursue research initiatives that are likely to support promotion.
The Research Initiation Award (RIA) provides release time and funds to female, assistant or associate professors to conduct research projects that will enhance their ability to compete successfully for external funding and achieve advancement in rank. One award will be granted in each of the years 2012, 2013, 2014 and 2015. The successful applicant will be awarded a total grant of $7,500 and three credits of release time each semester for the two year period of the award. The RIA provides funds for adjunct faculty to cover the 3 credits of release time. The 2012 award winner was Dr. Sarah Ewing, Department of Biology.
The award application is available to full-time, tenure-track, female faculty at the associate or assistant level with appointments in Biology, Chemistry, Computer & Information Science, Electrical & Computer Engineering, Environmental Science, Mathematics, Mechanical Engineering, Physics, Psychology and Software Engineering.
Successful proposals will define a project for which preliminary data can be obtained within a two year period; provide a self-contained account of what will be done; demonstrate the likelihood of a significant contribution to the field; and show strong potential to result in publication and presentations. One award will be granted in each of years 2-5 of the Gannon NSF PAID funding (i.e., a total of four awards during the five year period).
Proposals are reviewed by an ad-hoc committee appointed by the Gannon University NSF PAID Steering Committee. The review committee will be composed of senior faculty across multiple disciplines. The Steering Committee makes the final determination based on award recommendations of the review committee. Decisions will be made in early April.
Award recipients are required to report on the outcomes of their research. Progress reports should include details about research work, new grant proposals submitted, presentations, papers, collaborations, and other related scholarship.
The main body of the proposal must be no more than 2 pages including any pictures, graphs and tables. An additional page may be used for a bibliography. The proposal should include the following:
The budget should be no more than one page and should include a list of costs and a narrative justification. Funds may be requested for capital equipment, supplies, support of a graduate research assistant during any part of the year, summer undergraduate assistant salary, research expendables, and other expenses as justified.
Both the department chair and the Dean must sign a statement indicating that the three credits of release time each semester for two years will be granted to the award recipient.
Attach a two page CV which includes select papers and publications from the past 5 years.
An electronic version of the proposal is due to Weslene Tallmadge, Department of Chemistry, on or before February 28. You will receive an email confirmation acknowledging receipt of your proposal.
The strategy draws on the success of the following ADVANCE programs:
2012, Sarah Ewing, Department of Biology, Assistant Professor, http://www.gannon.edu/FacultyProfiles.aspx?profile=ewing003
Title: Effect of Manganese on Dopamine Metabolism and Dopaminergic Cell Toxicity
Statement of Research Objectives and Background and Significance
Parkinson’s disease (PD) is a progressive neurodegenerative disorder pathologically characterized by loss of dopamine-producing neurons in the substantia nigra pars compacta (SNpc) of the brain (1-3). Loss of dopamine production and signaling is responsible for many symptoms associated with the disease including resting tremor, rigidity, bradykinesia and postural instability (1-3). Despite vast efforts, the causes of PD and specific death of dopamine-producing neurons in the SNpc are still poorly understood (1-3). Many theories have been proposed to explain the etiology of PD including one called the “catecholamine/catecholaldehyde hypothesis” (1, 3-4). This hypothesis suggests dopamine and its metabolism are toxic because of production and accumulation of toxic metabolites, specifically, 3, 4–dihydroxylphenylacetaldehyde (DOPAL). DOPAL accumulation occurs particularly in response to mitochondrial dysfunction and oxidative stress, which inhibits further degradation to the less toxic metabolite, 3, 4-dihydroxyphenylglycolaldehyde (DOPAC) (1, 2, 4-7). Evidence has also led scientists to look for an environmental role in PD. Rural living, farming as an occupation, drinking well water, and pesticide exposure have all been associated with an increase in one’s susceptibility for developing sporadic PD (2). Exposure to high levels of manganese through mining, welding or exposure to pesticides containing manganese (Maneb) also results in a Parkinsonism-like disease (8-10). Many of these environmental agents including manganese elicit their effects in dopaminergic cells by blocking mitochondrial function and inducing oxidative stress (1, 2, 11-14).
The overall objective of this proposal is to investigate the effects of manganese on dopamine (DA) metabolism and toxicity in dopaminergic cells. Specifically, we hypothesize manganese has the ability to 1) elicit increased levels of DOPAL in dopaminergic cells and 2) increase dopaminergic cell toxicity when combined with elevated levels of DA or DOPAL compared to treatment with DA and/or DOPAL alone.
To address these hypotheses I propose the following specific aims:
The results of this study will provide the first evidence linking manganese to DOPAL levels in dopaminergic cells and further elucidate the effects of manganese on DA-induced toxicity in these cells. These findings could therefore contribute to our overall understanding of the mechanism through which manganese elicits neuronal cell toxicity and a potential means through which manganese may contribute to the etiology of Parkinson’s disease.
Lin Zhao, Department of Electrical and Computer
Engineering, Associate Professor, http://www.gannon.edu/FacultyProfiles.aspx?profile=zhao001
Title: Doubly-Fed-Induction-Generator Modeling and
Control for Wind Energy Harvesting
Statement of Research Objectives and Background and
USA Department of Energy (DOE) has initiated "20 percent wind
energy by 2030" in response to the energy crisis and finding
alternative/renewable energy resources. For large scale wind farms,
variable-speed generators (including DFIG) are widely used due to
their better controllability and low maintenance cost. However,
issues and challenges are still present in the research areas of
the modeling, analysis and control of DFIG. The proposed project is
to develop accurate dynamic models of DFIG and a HiTL system of
DFIG. Upon completion of the project, variant operation and control
techniques of the DFIG wind turbine will be able to be simulated
with the virtual model in real time. The developed HiTL system will
act as a down-sized wind farm in a lab environment to test the
feasibility and controllability of different types of control
strategies and fault-ride-thorough techniques.
The overall objectives of this proposal are to:
The significance of the proposed research has three folds: